Stabilin 2 (STAB2) anticorps

N° du produit ABIN6566765

Cet anticorps Lapin Polyclonal détecte spécifiquement dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Stabilin 2 (STAB2) anticorps (ABIN6566765)

Antigène: Stabilin 2 (STAB2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Purification: Affinity purification

Immunogène: Recombinant protein of human STAB2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: Stabilin 2 (STAB2)

Autre désignation: STAB2

Sujet:

Synonyms: 190 kDa form stabilin-2,190 kDa hyaluronan receptor for endocytosis,EGF-like,FAS1 EGF-like and X-link domain-containing adhesion molecule 2,Fasciclin,FEEL-2,FEEL2,FELL,FEX2,HARE,Hyaluronan receptor for endocytosis,laminin-type EGF-like and link domain-containing scavenger receptor 2,link domain-containing scavenger receptor 2,STAB-2,Stab2,STAB2

Background: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.

Poids moléculaire:

Observed_MW: 277kDa

Calculated_MW: 276kDa

ID gène: 55576

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process