KIF14 anticorps

N° du produit ABIN6566849

Détail du produit anti-KIF14 anticorps

Antigène: KIF14 (Kinesin Family Member 14 (KIF14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF14 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human KIF14 (NP_055690.1).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KIF14

Antigène: KIF14 (Kinesin Family Member 14 (KIF14))

Autre désignation: KIF14 (KIF14 Produits)

Synonymes: anticorps wu:fi16h07, anticorps si:dkey-39e8.3, anticorps KIF14, anticorps D1Ertd367e, anticorps E130203M01, anticorps kinesin family member 14, anticorps kinesin-like protein KIF14, anticorps KIF14, anticorps kif14, anticorps LOC100641544, anticorps Kif14

Sujet: This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 190kDa

Calculated_MW: 186kDa

ID gène: 9928

UniProt: Q15058