Cadherin 4 anticorps

N° du produit ABIN6566983

L’anticorps Lapin Polyclonal anti-Cadherin 4 a été validé pour WB. Il convient pour détecter Cadherin 4 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Cadherin 4 anticorps (ABIN6566983)

Antigène: Cadherin 4 (CDH4)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cadherin 4 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human CDH4

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cadherin 4

Antigène: Cadherin 4 (CDH4)

Autre désignation: R-Cadherin

Sujet:

Synonyms: CADH4,Cadherin 4,Cadherin-4,cdh4,R CAD,R-CAD,R-cadherin,Retinal cadherin

Background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 100kDa

Calculated_MW: 92kDa/100kDa

ID gène: 1002

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size