RIN2 anticorps

N° du produit ABIN6568165

Cet anticorps anti-RIN2 est un anticorps Lapin Polyclonal détectant RIN2 dans WB. Adapté pour Humain et Souris.

Aperçu rapide pour RIN2 anticorps (ABIN6568165)

Antigène: RIN2 (Ras and Rab Interactor 2 (RIN2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIN2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RIN2 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human RIN2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RIN2

Antigène: RIN2 (Ras and Rab Interactor 2 (RIN2))

Autre désignation: RIN2

Sujet:

Synonyms: MACS ,RAB5 interacting protein 2,Ras and Rab interactor 2,RAS association (RalGDS/AF-6) domain containing protein JC265,Ras association domain family 4,Ras inhibitor JC265,Ras interaction/interference protein 2,RASSF4,RIN 2,RIN2,RIN2

Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 120kDa

Calculated_MW: 100kDa/105kDa

ID gène: 54453

UniProt: Q8WYP3