POT1 anticorps

N° du produit ABIN6568518

L’anticorps Lapin Polyclonal anti-POT1 a été validé pour WB et IHC. Il convient pour détecter POT1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour POT1 anticorps (ABIN6568518)

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-POT1 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human POT1

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur POT1

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Autre désignation: POT1

Sujet:

Synonyms: DKFZP586D211,hPot 1,hPot1,POT 1,POT1,POT1 like telomere end-binding protein,POT1 protection of telomeres 1 homolog,POT1-like telomere end-binding protein,POTE1,Protection of telomeres 1,Protection of telomeres 1 homolog (S. pombe),Protection of telomeres protein 1

Background: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Poids moléculaire:

Observed_MW: 75kDa

Calculated_MW: 60kDa/71kDa

ID gène: 25913

UniProt: Q9NUX5

Pathways: Cycle Cellulaire, Telomere Maintenance