Importin 5 anticorps

N° du produit ABIN6569027

Cet anticorps Lapin Polyclonal détecte spécifiquement Importin 5 dans WB et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Importin 5 anticorps (ABIN6569027)

Antigène: Importin 5 (IPO5)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Importin 5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Importin 5 anticorps

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human IPO5 (NP_002262.3).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Importin 5

Antigène: Importin 5 (IPO5)

Autre désignation: IPO5

Sujet: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Poids moléculaire:

Observed_MW: 125kDa

Calculated_MW: 116kDa/123kDa/125kDa

ID gène: 3843

UniProt: O00410

Pathways: Protein targeting to Nucleus