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SEC63 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement SEC63 dans WB et IHC (p). Il présente une réactivité envers Humain.
N° du produit ABIN657052

Aperçu rapide pour SEC63 anticorps (N-Term) (ABIN657052)

Antigène

Voir toutes SEC63 Anticorps
SEC63 (SEC63 Homolog (SEC63))

Reactivité

  • 22
  • 9
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 18
  • 4
Lapin

Clonalité

  • 20
  • 2
Polyclonal

Conjugué

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SEC63 est non-conjugé

Application

  • 22
  • 12
  • 9
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB32397
  • Épitope

    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 139-168, N-Term

    Homologie

    M

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This SEC63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the N-terminal region of human SEC63.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. IHC-P: 1:10~50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Date de péremption

    6 months
  • Antigène

    SEC63 (SEC63 Homolog (SEC63))

    Autre désignation

    SEC63

    Sujet

    The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

    Poids moléculaire

    87997

    NCBI Accession

    NP_009145

    UniProt

    Q9UGP8

    Pathways

    ER-Nucleus Signaling
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