RENT2/UPF2 anticorps

N° du produit ABIN6570914

L’anticorps Lapin Polyclonal anti-RENT2/UPF2 a été validé pour WB et IHC. Il convient pour détecter RENT2/UPF2 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour RENT2/UPF2 anticorps (ABIN6570914)

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RENT2/UPF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RENT2/UPF2 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human UPF2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RENT2/UPF2

Antigène: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Autre désignation: UPF2

Sujet:

Synonyms: DKFZp434D222,hUpf2,KIAA1408,MGC138834,MGC138835,Nonsense mRNA reducing factor 2,Regulator of nonsense transcripts 2,RENT2,RENT2,Smg 3,Smg 3 homolog nonsense mediated mRNA decay factor,Up-frameshift suppressor 2 homolog,UPF2,UPF2 regulator of nonsense transcripts homolog,UROC1,Urocanate hydratase,Yeast Upf2p homolog

Background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.

Poids moléculaire:

Observed_MW: 148kDa

Calculated_MW: 66kDa/147kDa

ID gène: 26019

UniProt: Q9HAU5