RENT2/UPF2 anticorps (Middle Region)
Aperçu rapide pour RENT2/UPF2 anticorps (Middle Region) (ABIN955462)
Antigène
Voir toutes RENT2/UPF2 (UPF2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 633-660, Middle Region
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Specificité
- This antibody detects UPF2 / RENT2 (Center).
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Protein A column followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 633-660 amino acids from the Central region of human UPF2
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
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Autre désignation
- UPF2 / RENT2
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Sujet
- UPF2 is a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p.Synonyms: KIAA1408, Regulator of nonsense transcripts 2, Up-frameshift suppressor 2 homolog
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ID gène
- 26019
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NCBI Accession
- NP_056357
Antigène
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