SPAG8 anticorps

N° du produit ABIN6571917

L’anticorps Lapin Polyclonal anti-SPAG8 a été validé pour WB. Il convient pour détecter SPAG8 dans des échantillons de Souris et Rat.

Aperçu rapide pour SPAG8 anticorps (ABIN6571917)

Antigène: SPAG8 (Sperm Associated Antigen 8 (SPAG8))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPAG8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPAG8 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human SPAG8

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SPAG8

Antigène: SPAG8 (Sperm Associated Antigen 8 (SPAG8))

Autre désignation: SPAG8

Sujet:

Synonyms: BS 84,CILD28,HSD 1,HSD-1,HSD1,hSMP1,MGC26201,MH SPAG8,OTTHUMP00000021352,OTTMUSP00000032209,SMP-1,SMP1,SPAG3,SPAG8,SPAG8,Sperm associated antigen 8,Sperm associated antigen 8 like protein,Sperm membrane protein 1,Sperm membrane protein BS-84,Sperm-associated antigen 8,Testicular tissue protein Li 177

Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

Poids moléculaire:

Observed_MW: 45kDa

Calculated_MW: 44kDa/51kDa/53kDa

ID gène: 26206

UniProt: Q99932