PRCP anticorps (N-Term)

N° du produit ABIN657308

L’anticorps Lapin Polyclonal anti-PRCP a été validé pour WB et IHC (p). Il convient pour détecter PRCP dans des échantillons de Humain.

Aperçu rapide pour PRCP anticorps (N-Term) (ABIN657308)

Antigène: PRCP (Prolylcarboxypeptidase (PRCP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRCP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32742

Détail du produit anti-PRCP anticorps

Épitope: AA 114-143, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PRCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of human PRCP.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PRCP

Antigène: PRCP (Prolylcarboxypeptidase (PRCP))

Autre désignation: PRCP

Sujet: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH , but the enzyme activity is retained with some substrates at neutral pH . This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].

Poids moléculaire: 55800

NCBI Accession: NP_005031, NP_955450

UniProt: P42785