RFC4 anticorps

N° du produit ABIN190320

Cet anticorps anti-RFC4 est un anticorps Souris Monoclonal détectant RFC4 dans WB et IF/ICC. Adapté pour Humain.

Aperçu rapide pour RFC4 anticorps (ABIN190320)

Antigène: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RFC4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Clone: 1320

Détail du produit anti-RFC4 anticorps

Fonction: Anti-Replication Factor C p37 Mouse Monoclonal Antibody

Specificité: This antibody recognizes the p37 subunit of human and yeast (S. cerevisiae) Replication Factor C (RFC). RFC is a heteropentameric protein consisting of p140, p40, p38, p37, and p36 subunits, RFC participates in targeting DNA polymerase delta processivity factor (PCNA) on to a primed DNA template during DNA synthesis and repair. RFC has also been associated with DNA repair in conjunction with a PCNA-like heterotrimer of Hus1, Rad1, and Rad9.

Réactivité croisée: Humain, Saccharomyces cerevisiae

Immunogène: Recombinant protein corresponding to the p37 subunit of human Replication Factor C expressed in E. coli.

Isotype: IgG2b

Information d'application

Indications d'application: Immunoblotting: use at 1:2,000 dilution. A band of 37 kD is detected.
Positive controls: HeLa cell lysate.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Dilute in PBS or medium which is identical to that used in the assay system.

Concentration: Lot specific

Buffer: PBS, pH 7.4

Stock: -80 °C

Stockage commentaire: This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze-thaw cycles.

Détails sur RFC4

Antigène: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Autre désignation: RFC4 / RFC37

Sujet: Replication factor C subunit 2,The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity). {ECO:0000250}.,Nucleus,Activator 1 40 kDa subunit, A1 40 kDa subunit, Activator 1 subunit 2, Replication factor C 40 kDa subunit, RF-C 40 kDa subunit, RFC40

UniProt: P35250

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA