Surfactant Protein C anticorps (C-Term)

N° du produit ABIN657607

Cet anticorps Lapin Polyclonal détecte spécifiquement Surfactant Protein C dans WB, IF et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Surfactant Protein C anticorps (C-Term) (ABIN657607)

Antigène: Surfactant Protein C (SFTPC)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Surfactant Protein C est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB33577

Détail du produit anti-Surfactant Protein C anticorps

Épitope: AA 144-173, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the C-terminal region of human SFTPC.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:2000. WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: SFTPC Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur Surfactant Protein C

Antigène: Surfactant Protein C (SFTPC)

Autre désignation: SFTPC

Sujet: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Poids moléculaire: 21053

ID gène: 6440

NCBI Accession: NP_001165828, NP_001165881, NP_003009

UniProt: P11686