Metabotropic Glutamate Receptor 6 anticorps (AA 369-398)

N° du produit ABIN657657

Cet anticorps anti-Metabotropic Glutamate Receptor 6 est un anticorps Lapin Polyclonal détectant Metabotropic Glutamate Receptor 6 dans WB. Adapté pour Humain.

Aperçu rapide pour Metabotropic Glutamate Receptor 6 anticorps (AA 369-398) (ABIN657657)

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 6 est non-conjugé

Application: Western Blotting (WB)

Clone: RB33716

Détail du produit anti-Metabotropic Glutamate Receptor 6 anticorps

Épitope: AA 369-398

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GRM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the Central region of human GRM6.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: GRM6 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur Metabotropic Glutamate Receptor 6

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Autre désignation: GRM6

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Poids moléculaire: 95468

ID gène: 2916

NCBI Accession: NP_000834

UniProt: O15303