C4B anticorps (AA 655-684)

N° du produit ABIN657906

Cet anticorps anti-C4B est un anticorps Lapin Polyclonal détectant C4B dans WB. Adapté pour Humain.

Aperçu rapide pour C4B anticorps (AA 655-684) (ABIN657906)

Antigène: C4B (C4b) (Complement Component C4b (C4b))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C4B est non-conjugé

Application: Western Blotting (WB)

Clone: RB33642

Détail du produit anti-C4B anticorps

Épitope: AA 655-684

Homologie: H

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This C4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 655-684 amino acids from the Central region of human C4B.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: C4B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur C4B

Antigène: C4B (C4b) (Complement Component C4b (C4b))

Autre désignation: C4B

Sujet: This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.

Poids moléculaire: 192785

ID gène: 721

NCBI Accession: NP_001002029, NP_001239133, NP_009224

UniProt: P0C0L4

Pathways: Système du Complément