Endothelin 1 anticorps (AA 131-180)

N° du produit ABIN6579220

Cet anticorps anti-Endothelin 1 Polyclonal Lapin (ABIN6579220) détecte spécifiquement Endothelin 1 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Endothelin 1 anticorps (AA 131-180) (ABIN6579220)

Antigène: Endothelin 1 (EDN1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endothelin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Endothelin 1 anticorps

Épitope: AA 131-180

Fonction: ET-1 Antibody

Specificité: ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180

Isotype: IgG

Information d'application

Indications d'application: IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Endothelin 1

Antigène: Endothelin 1 (EDN1)

Autre désignation: EDN1

Sujet:

Synonyms: EDN1, Endothelin-1, Preproendothelin-1, PPET1

Background: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Gene Name: EDN1

Protein Name: Endothelin-1

Poids moléculaire: 24 kDa

ID gène: 1906

OMIM: 131240

UniProt: P05305

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size