RUNX2 anticorps (AA 201-250)

N° du produit ABIN6579238

L’anticorps anti-RUNX2 Polyclonal Lapin est utilisé pour la détection de RUNX2 dans des échantillons de Humain, Souris, Rat et Chien. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour RUNX2 anticorps (AA 201-250) (ABIN6579238)

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-RUNX2 anticorps

Épitope: AA 201-250

Fonction: RUNX2 Antibody

Specificité: RUNX2 Polyclonal Antibody detects endogenous levels of RUNX2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human RUNX2. AA range:201-250

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-200 WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur RUNX2

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Autre désignation: RUNX2

Sujet:

Synonyms: RUNX2, AML3, CBFA1, OSF2, PEBP2A, Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, CBF-alpha-1, Oncogene AML-3Osteoblast-specific transcription factor 2, OSF-2, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEA2-alpha A, PEBP2-alpha A, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit

Background: This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016],

Gene Name: RUNX2

Protein Name: Runt-related transcription factor 2

Poids moléculaire: 56 kDa

ID gène: 860

OMIM: 600211

UniProt: Q13950