K-RAS anticorps (AA 150-189)

N° du produit ABIN6579257

Cet anticorps Lapin Polyclonal détecte spécifiquement K-RAS dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour K-RAS anticorps (AA 150-189) (ABIN6579257)

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp K-RAS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-K-RAS anticorps

Épitope: AA 150-189

Fonction: K-Ras Antibody

Specificité: K-Ras Polyclonal Antibody detects endogenous levels of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRAS. AA range:150-189

Isotype: IgG

Information d'application

Indications d'application: IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur K-RAS

Antigène: K-RAS (KRAS) (GTPase Kras (KRAS))

Autre désignation: KRAS

Sujet:

Synonyms: GTPase KRas (K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]

Background: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],

Gene Name: KRAS

Protein Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Poids moléculaire: 21 kDa

ID gène: 3845

OMIM: 190070

UniProt: P01116