APOA1 anticorps (AA 81-130)
Aperçu rapide pour APOA1 anticorps (AA 81-130) (ABIN6579270)
Antigène
Voir toutes APOA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 81-130
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Fonction
- ApoA-I Antibody
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Specificité
- ApoA-I Polyclonal Antibody detects endogenous levels of ApoA-I protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from the Internal region of human APOA1. AA range:81-130
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- APOA1 (Apolipoprotein A-I (APOA1))
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Autre désignation
- APOA1
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Sujet
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Synonyms: APOA1, Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1
Background: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015],
Gene Name: APOA1
Protein Name: Apolipoprotein A-I
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Poids moléculaire
- 30 kDa
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ID gène
- 335
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OMIM
- 107680
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UniProt
- P02647
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
Antigène
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