IL5RA anticorps (AA 41-90)

N° du produit ABIN6579374

Cet anticorps Lapin Polyclonal détecte spécifiquement IL5RA dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IL5RA anticorps (AA 41-90) (ABIN6579374)

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL5RA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-IL5RA anticorps

Épitope: AA 41-90

Fonction: IL-5Rα Antibody

Specificité: IL-5Rα Polyclonal Antibody detects endogenous levels of IL-5Rα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the N-terminal region of human IL5RA. AA range:41-90

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur IL5RA

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Autre désignation: IL5RA

Sujet:

Synonyms: IL5RA, IL5R, Interleukin-5 receptor subunit alpha, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5R-alpha, IL-5RA, CDw125, CD125

Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011],

Gene Name: IL5RA

Protein Name: Interleukin-5 receptor subunit alpha

Poids moléculaire: 47 kDa

ID gène: 3568

UniProt: Q01344

Pathways: Signalistation JAK/STAT