Neuropilin 1 anticorps (AA 321-370)
Aperçu rapide pour Neuropilin 1 anticorps (AA 321-370) (ABIN6579407)
Antigène
Voir toutes Neuropilin 1 (NRP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 321-370
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Fonction
- Neuropilin Antibody
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Specificité
- Neuropilin Polyclonal Antibody detects endogenous levels of Neuropilin protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from the Internal region of human NRP1. AA range:321-370
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Neuropilin 1 (NRP1)
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Autre désignation
- NRP1
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Sujet
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Synonyms: NRP1, NRP, VEGF165R, Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD304
Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
Gene Name: NRP1
Protein Name: Neuropilin-1
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Poids moléculaire
- 103 kDa
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ID gène
- 8829
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UniProt
- O14786
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Pathways
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
Antigène
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