CR1L anticorps (AA 300-350)

N° du produit ABIN6579446

L’anticorps anti-CR1L Polyclonal Lapin est utilisé pour la détection de CR1L dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour CR1L anticorps (AA 300-350) (ABIN6579446)

Antigène: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CR1L est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CR1L anticorps

Épitope: AA 300-350

Fonction: CD35 Antibody

Specificité: CD35 Polyclonal Antibody detects endogenous levels of CD35

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human CR1/CR1L. AA range:300-350 & 740-790

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CR1L

Antigène: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Autre désignation: CR1/CR1L

Sujet:

Synonyms: complement component (3b/4b) receptor 1/2 (Knops blood group)

Background: This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants

Protein Name: CD35

Poids moléculaire: '220 kDa

ID gène: 1378, 1379

UniProt: P17927

Pathways: Système du Complément