SIGLEC8 anticorps (AA 81-130)

N° du produit ABIN6579554

Cet anticorps Lapin Polyclonal détecte spécifiquement SIGLEC8 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SIGLEC8 anticorps (AA 81-130) (ABIN6579554)

Antigène: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGLEC8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SIGLEC8 anticorps

Épitope: AA 81-130

Fonction: CD329 Antibody

Specificité: CD329 Polyclonal Antibody detects endogenous levels of CD329 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human SIGLEC8. AA range:81-130

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SIGLEC8

Antigène: SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))

Autre désignation: SIGLEC8

Sujet:

Synonyms: SIGLEC8, SAF2, Sialic acid-binding Ig-like lectin 8, Siglec-8, CDw329, Sialoadhesin family member 2, SAF-2, CD329

Background: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010],

Gene Name: SIGLEC8

Protein Name: Sialic acid-binding Ig-like lectin 8

Poids moléculaire: 54 kDa

ID gène: 27181

OMIM: 605639

UniProt: Q9NYZ4