Amphiregulin anticorps (AA 91-140)

N° du produit ABIN6579595

Cet anticorps Lapin Polyclonal détecte spécifiquement Amphiregulin dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Amphiregulin anticorps (AA 91-140) (ABIN6579595)

Antigène: Amphiregulin (AREG)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amphiregulin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Amphiregulin anticorps

Épitope: AA 91-140

Fonction: Amphiregulin Antibody

Specificité: Amphiregulin Polyclonal Antibody detects endogenous levels of Amphiregulin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human AREG/AREGB. AA range:91-140

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Amphiregulin

Antigène: Amphiregulin (AREG)

Autre désignation: AREG/AREGB

Sujet:

Synonyms: AREG, SDGF, AREGB, Amphiregulin, AR, Colorectum cell-derived growth factor, CRDGF

Background: The protein encoded byThis gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014],

Gene Name: AREG/AREGB

Protein Name: Amphiregulin

Poids moléculaire: 27 kDa

ID gène: 374, 727738

OMIM: 104640

UniProt: P15514

Pathways: Signalisation RTK, EGFR Signaling Pathway