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IL2RG anticorps

Cet anticorps anti-IL2RG est un anticorps Rat Monoclonal détectant IL2RG dans FACS. Adapté pour Humain et Chien.
N° du produit ABIN6579821

Aperçu rapide pour IL2RG anticorps (ABIN6579821)

Antigène

Voir toutes IL2RG Anticorps
IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivité

  • 74
  • 30
  • 26
  • 3
  • 1
Humain, Chien

Hôte

  • 56
  • 14
  • 13
  • 1
  • 1
  • 1
Rat

Clonalité

  • 60
  • 26
Monoclonal

Conjugué

  • 41
  • 11
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp IL2RG est non-conjugé

Application

  • 52
  • 38
  • 25
  • 10
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

TUGh4
  • Fonction

    Anti-Hu CD132 Purified

    Specificité

    The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.

    Réactivité croisée (Details)

    Human, Canine (Dog)

    Purification

    Purified by protein-G affinity chromatography.

    Pureté

    > 95 % (by SDS-PAGE)

    Immunogène

    Human CD132-transfected cell line

    Isotype

    IgG2b kappa
  • Indications d'application

    Flow cytometry: Recommended dilution: 1-4 μg/mL.

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Store at 2-8°C. Do not freeze.
  • Antigène

    IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

    Autre désignation

    CD132

    Sujet

    Interleukin 2 receptor subunit gamma,CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID). CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.,common gamma chain, IL2RG, SCIDX, IMD4

    ID gène

    3561

    UniProt

    P31785

    Pathways

    Signalistation JAK/STAT, Growth Factor Binding
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