DYRK2 anticorps (C-Term)

N° du produit ABIN657991

Cet anticorps Lapin Polyclonal détecte spécifiquement DYRK2 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour DYRK2 anticorps (C-Term) (ABIN657991)

Antigène: DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DYRK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB34467

Détail du produit anti-DYRK2 anticorps

Épitope: AA 521-549, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Mouse Dyrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of mouse Dyrk2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:1000. WB: 1:8000. IHC-P: 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Mouse Dyrk2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur DYRK2

Antigène: DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))

Autre désignation: Dyrk2

Sujet: Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).

Poids moléculaire: 66556

ID gène: 69181

NCBI Accession: NP_001014412

UniProt: Q5U4C9

Pathways: Regulation of Carbohydrate Metabolic Process