BMI1 anticorps

N° du produit ABIN659173

Cet anticorps Souris Monoclonal détecte spécifiquement BMI1 dans WB et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour BMI1 anticorps (ABIN659173)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 282CT3-7-6

Détail du produit anti-BMI1 anticorps

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This BMI1 monoclonal antibody is generated from mouse immunized with BMI1 recombinant protein.

Isotype: IgG1 kappa

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. WB: 1:100~250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: BMI1 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: BMI1

Sujet: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Poids moléculaire: 36949

ID gène: 648

NCBI Accession: NP_001190991, NP_005171

UniProt: P35226

Pathways: Cycle Cellulaire, Autophagy