CD40 Ligand anticorps

N° du produit ABIN6651981

Cet anticorps Hamster Monoclonal détecte spécifiquement CD40 Ligand dans FACS et IHC (p). Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour CD40 Ligand anticorps (ABIN6651981)

Antigène: CD40 Ligand (CD40LG)

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 Ligand est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MAB0712

Détail du produit anti-CD40 Ligand anticorps

Specificité: This antibody detects Mouse CD40 Ligand. Other species not tested. Species: Mouse.

Purification: Affinity Chromatography on Protein G

Immunogène: Mouse Th1 cells.

Isotype: IgG2

Information d'application

Indications d'application: Flow Cytometry: 1/100-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/300.

Restrictions: For Research Use only

Stockage

Buffer: PBS Stabilizers: None

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD40 Ligand

Antigène: CD40 Ligand (CD40LG)

Autre désignation: cd154,cd40l

Sujet: CD40 ligand (CD40L), also known as CD154, TNFSF5, TRAP or gp39, is a 260 amino acid type II transmembrane glycoprotein belonging to the TNF family. Murine CD40L consists of a 22 aa cytoplasmic domain, a 24 aa transmembrane domain, and 214 aa extracellular domain bearing a single glycosylation site. CD40L is expressed predominantly on activated CD4+ T lymphocytes, and also found in other types of cells, including NK cells, mast cells, basophils and eosinophils. Murine CD40L shares 78 % amino acid sequence identity with human CD40L. Native bioactive soluble CD40L exists. Soluble human trimeric CD40L secreted by stimulated T cells has been shown to be generated by proteolysis in the microsomes. Both membrane bound and soluble CD40L induce similar effects on B cells.

UniProt: P27548

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints