DKK1 anticorps (AA 32-266)

N° du produit ABIN6654082

L’anticorps Lapin Polyclonal anti-DKK1 a été validé pour WB et ELISA (Capture). Il convient pour détecter DKK1 dans des échantillons de Humain.

Aperçu rapide pour DKK1 anticorps (AA 32-266) (ABIN6654082)

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKK1 est non-conjugé

Application: Western Blotting (WB), ELISA (Capture)

Détail du produit anti-DKK1 anticorps

Épitope: AA 32-266

Purification: Antigen affinity purified

Immunogène: Amino acids T32-H266 from the human protein were used as the immunogen for the DKK1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the DKK1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,ELISA (Capture): 1-5 μg/mL (human recombinant protein)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the DKK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur DKK1

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Autre désignation: DKK1

Sujet: DKK1, Dickkopf-related protein 1, is a protein that in humans is encoded by the DKK1 gene. This gene encodes a protein that is a member of the dickkopf family. By genomic sequence analysis, determined that the DKK1 gene contains 4 exons. The DKK1 gene is mapped to 10q11.2 using FISH. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

UniProt: O94907

Pathways: Signalisation WNT, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation