Recombinant PLAP anticorps (full length)

N° du produit ABIN6654247

L’anticorps anti-PLAP Monoclonal Lapin est utilisé pour la détection de PLAP dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant PLAP anticorps (full length) (ABIN6654247)

Antigène: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PLAP est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: KSUP-2R

Détail du produit anti-PLAP anticorps

Épitope: full length

Fonction: Recombinant PLAP Antibody / Placental Alkaline Phosphatase (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogène: Recombinant full-length human protein was used as the immunogen for the recombinant PLAP antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant PLAP antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant PLAP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur PLAP

Antigène: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Autre désignation: PLAP

Sujet: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

UniProt: P05187