Elastin anticorps

N° du produit ABIN6654572

Cet anticorps anti-Elastin est un anticorps Lapin Monoclonal détectant Elastin dans IHC (p). Adapté pour Humain.

Aperçu rapide pour Elastin anticorps (ABIN6654572)

Antigène: Elastin (ELN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Elastin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ELN-3131R

Détail du produit anti-Elastin anticorps

Purification: Purified

Pureté: Protein A affinity chromatography

Immunogène: Recombinant full length human protein was used as the immunogen for the recombinant Elastin antibody.

Isotype: IgG kappa

Information d'application

Indications d'application: Titering of the recombinant Elastin antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant Elastin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur Elastin

Antigène: Elastin (ELN)

Autre désignation: Elastin

Sujet: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Pathways: Regulation of Actin Filament Polymerization