BMI1 anticorps (AA 142-326)

N° du produit ABIN6654676

L’anticorps Souris Monoclonal anti-BMI1 a été validé pour IHC (p). Il convient pour détecter BMI1 dans des échantillons de Humain.

Aperçu rapide pour BMI1 anticorps (AA 142-326) (ABIN6654676)

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BMI1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: BMI1-2689

Détail du produit anti-BMI1 anticorps

Épitope: AA 142-326

Purification: Purified

Pureté: Protein G affinity chromatography

Immunogène: A portion of amino acids 142-326 from the human protein was used as the immunogen for the BMI1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the BMI1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the BMI1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur BMI1

Antigène: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Autre désignation: BMI1

Sujet: The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies.

Pathways: Cycle Cellulaire, Autophagy