Elastase 3B anticorps (AA 82-238)

N° du produit ABIN6655004

Cet anticorps anti-Elastase 3B est un anticorps Lapin Monoclonal détectant Elastase 3B dans IHC (p). Adapté pour Humain.

Aperçu rapide pour Elastase 3B anticorps (AA 82-238) (ABIN6655004)

Antigène: Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Elastase 3B est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CELA3B-2809R

Détail du produit anti-Elastase 3B anticorps

Épitope: AA 82-238

Purification: Purified

Pureté: Protein A affinity chromatography

Immunogène: A recombinant partial protein (aa 82-238) was used as the immunogen for the recombinant CELA3B antibody.

Isotype: IgG kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant CELA3B antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant CELA3B antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur Elastase 3B

Antigène: Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

Autre désignation: CELA3B / Elastase 3B

Sujet: This MAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function.