CD8 alpha anticorps (APC)

N° du produit ABIN6655184

N° du produit (Fournisseur): 200-326-m64

Cet anticorps anti-CD8 alpha est un anticorps Souris Monoclonal détectant CD8 alpha dans FACS. Adapté pour Humain.

Aperçu rapide pour CD8 alpha anticorps (APC) (ABIN6655184)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8 alpha est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: RPA-T8

Détail du produit anti-CD8 alpha anticorps (APC)

N° du produit (Fournisseur): 200-326-m64

Fournisseur: Rockland

Fonction: CD8 APC Antibody

Réactivité croisée (Details): Reactivity is observed against human CD8, chimpanzee, baboon, cynomolgus, rhesus, and ooty mangabey.

Purification: Allophycocyanin conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8.

Stérilité: Sterile filtered

Immunogène: Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.

Isotype: IgG1 kappa

Labeling Ratio: 1-2

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 10 μL/10^6 cells (0.25 μg)

Commentaires:

Anti-CD8 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.1 % Gelatin

Preservative: 0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Date de péremption: 6 months

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8A

Sujet:

Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL

Background: CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.

Gene Name: CD8

ID gène: 925

NCBI Accession: NP_001139345

UniProt: P01732

Pathways: TCR Signaling