SMAD6 anticorps

N° du produit ABIN6655220

N° du produit (Fournisseur): 200-401-i15

Cet anticorps anti-SMAD6 est un anticorps Lapin Polyclonal détectant SMAD6 dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour SMAD6 anticorps (ABIN6655220)

Antigène: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SMAD6 anticorps

N° du produit (Fournisseur): 200-401-i15

Fournisseur: Rockland

Fonction: SMAD6 Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with Anti-SMAD6 from Human, Mouse, New World monkey, Rat and Sheep based on 100 % homology with the immunizing sequence.

Purification: Anti-SMAD6 Antibody was purified by Protein G chromatography.

Immunogène: SMAD6 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to two internal amino acid sequences in the human SMAD6 protein.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry_Dilution: 5-10 μg/mL

Western_Blot_Dilution: 1-3 μg/mL

Commentaires:

Anti-SMAD6 antibody is tested for use in IHC, IF, and WB. Expect a band approximately 53kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

Preservative: 0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur SMAD6

Antigène: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Autre désignation: SMAD6

Sujet:

Synonyms: MADH6

Background: Anti-SMAD6 antibody detects human SMAD6. SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and 7). SMAD1, 5, 8 and 9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature. Anti-SMAD6 antibody is ideal for investigators involved kinase and phosphatase and NFkappaB research.

Gene Name: SMAD6

ID gène: 4091

NCBI Accession: NP_001136333

UniProt: O43541

Pathways: Chromatin Binding