BIRC7 anticorps

N° du produit ABIN6655300

N° du produit (Fournisseur): 200-301-h90

L’anticorps Souris Monoclonal anti-BIRC7 a été validé pour WB, IF et FM. Il convient pour détecter BIRC7 dans des échantillons de Humain.

Aperçu rapide pour BIRC7 anticorps (ABIN6655300)

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BIRC7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Clone: 88C570

Détail du produit anti-BIRC7 anticorps

N° du produit (Fournisseur): 200-301-h90

Fournisseur: Rockland

Fonction: Livin Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with Livin from human based on 100 % homology with the immunizing sequence.

Purification: Anti-Livin Antibody was purified by Protein G chromatography.

Immunogène: Livin Antibody was produced in mice prepared by repeated immunizations with recombinant human protein, Livin.

Isotype: IgG1 kappa

Information d'application

Indications d'application:

IF_Microscopy_Dilution: 2-5 μg/mL

Western_Blot_Dilution: 1-2 μg/mL

Commentaires:

Anti-Livin antibody is tested for use in IF/ICC and WB. Expect a band approximately 30kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

Preservative: 0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur BIRC7

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Autre désignation: Livin

Sujet:

Synonyms: KIAP, LIVIN, MLIAP, RNF50, BIRC7, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, ML-IAP, RING finger protein 50

Background: Anti-Livin BIRC7 KIAP antibody detects human Livin BIRC7 KIAP. The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. Recently a novel human inhibitor of apoptosis protein (IAP) family member termed Livin or ML-IAP, which contains a single baculoviral IAP repeat (BIR) domain and a COOH-terminal RING finger domain, has been identified. Livin gene has two splicing variants that contain open reading frames of 298 and 280 amino acids and both contained a single copy of baculovirus IAP repeat (BIR) and RING domain. Both of the isoforms inhibit TNFa induced apoptosis in Jurkat cells. Livin expression is low in adult tissues. It is relatively expressed at a higher level in developmental tissues and in many cancer cells. Anti-Livin BIRC7 KIAP antibody is ideal for investigators invovled in apoptosis reasearch.

Gene Name: BIRC7

ID gène: 79444

NCBI Accession: NP_071444

UniProt: Q96CA5