LOX anticorps

N° du produit ABIN6655735

N° du produit (Fournisseur): 100-401-h91

L’anticorps Lapin Polyclonal anti-LOX a été validé pour WB, IHC, IF, IP et FM. Il convient pour détecter LOX dans des échantillons de Humain.

Aperçu rapide pour LOX anticorps (ABIN6655735)

Antigène: LOX (Lysyl Oxidase (LOX))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LOX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Détail du produit anti-LOX anticorps

N° du produit (Fournisseur): 100-401-h91

Fournisseur: Rockland

Fonction: Lysyl Oxidase Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with Anti-Lysyl Oxidase from human, bovine, chimpanzee, mouse and rat 100 % homology with the immunizing sequence.

Purification: Anti-Lysyl Oxidase Antibody is crude rabbit sera.

Immunogène: Lysyl Oxidase Antibody was produced from whole rabbit serum prepared by repeated immunizations with the human protein Lysyl Oxidase at an internal amino acid sequence.

Isotype: IgG

Information d'application

Indications d'application:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 1:100

IF_Microscopy_Dilution: User Optimized

Western_Blot_Dilution: 1:250-1:1000

Commentaires:

Anti-Lysyl Oxidase antibody has been tested in WB, ICC/IF, IHC-F, IHC-P, IP. Expect a band approximately 31kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Optional[Buffer]: 50 % (v/v) Glycerol ,0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur LOX

Antigène: LOX (Lysyl Oxidase (LOX))

Autre désignation: Lysyl Oxidase

Sujet:

Synonyms: Lysyl oxidase, LOX, Protein-lysine-6 oxidase

Background: Anti-Lysyl Oxidase antibody detects human Lysyl Oxidase. Lysyl Oxidase (LOX) belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of ECM. Localized both in the cytosol and nucleus, it catalyzes the oxidation and deamination of epsilon-NH2 group of lysine and hydroxylysine residues to alpha-aminoadipic-delta-semialdehyde. This is the first step that initiates the covalent cross-linking of collagen and tropoelastin resulting in the formation of insoluble collagen and elastic fibers in the extracellular matrix. LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. Deficiency of LOX is seen in certain carcinomas and 3X-linked recessive human connective tissue disorders-Cutis Laxa. Anti-Lysyl Oxidase antibody is ideal for investigators involved in cytokines and growth factors.

Gene Name: LOX

ID gène: 4015

NCBI Accession: NP_002308

UniProt: P28300

Pathways: SARS-CoV-2 Protein Interactome