SIRT5 anticorps

N° du produit ABIN6656505

N° du produit (Fournisseur): 200-401-i14

Cet anticorps Lapin Polyclonal détecte spécifiquement SIRT5 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour SIRT5 anticorps (ABIN6656505)

Antigène: SIRT5 (Sirtuin 5 (SIRT5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SIRT5 anticorps

N° du produit (Fournisseur): 200-401-i14

Fournisseur: Rockland

Fonction: SIRT5 Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with Anti-SIRT5 from human, mouse and rat based on 100 % homology with the immunizing sequence.

Purification: Anti-SIRT5 Antibody was purified by Protein G chromatography.

Immunogène: SIRT5 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to internal amino acids of human SIRT5 .

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 1-3 μg/mL

Commentaires:

Anti-SIRT5 Antibody is tested for use in WB. Expect a band approximately 37kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur SIRT5

Antigène: SIRT5 (Sirtuin 5 (SIRT5))

Autre désignation: SIRT5

Sujet:

Synonyms: SIR2L5

Background: Anti-SIRT5 Antibody detects human SIRT5. SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones. Anti-SIRT5 Antibody is ideal for investigators involved in Epigenetic , chromatin, or enzyme research.

Gene Name: SIRT5

ID gène: 23408

NCBI Accession: NP_001180196

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interactome