AQP2 anticorps (C-Term)

N° du produit ABIN6656925

N° du produit (Fournisseur): 600-401-e90

Cet anticorps Lapin Polyclonal détecte spécifiquement AQP2 dans WB, IHC, IF et FM. Il présente une réactivité envers Rat.

Aperçu rapide pour AQP2 anticorps (C-Term) (ABIN6656925)

Antigène: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AQP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Détail du produit anti-AQP2 anticorps

Épitope: C-Term

N° du produit (Fournisseur): 600-401-e90

Fournisseur: Rockland

Fonction: Aquaporin 2 Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with Aquaporin 2 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

Purification: Anti-Aquaporin 2 Antibody was purified by affinity chromatography.

Stérilité: Sterile filtered

Immunogène: Aquaporin 2 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of rat aquaporin 2.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry_Dilution: 1:200

IF_Microscopy_Dilution: 1:400

Western_Blot_Dilution: 1:1000 - 1:4000

Commentaires:

Anti-Aquaporin 2 Antibody is tested for use in WB, IHC, and IF microscopy. Expect a band approximately ~28.5kDa on specific lysates. May detect larger glycosylated bands ~35-50kDa. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur AQP2

Antigène: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Autre désignation: Aquaporin 2

Sujet:

Synonyms: AQP2, AQP-CD, AQPCD, WCH CD, Aquaporin-2, AQP-2, ADH water channel, Aquaporin-CD, QP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct

Background: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins. Aquaporin 2 is the vasopressin-regulated water channel of the apical membrane of collecting duct cells. It is located in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes. When it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that cause AQP2 containing vesicles to fuse with the plasma membrane so the AQP2 can be used by the cell. Defects in AQP2 area cause of an autosomal dominant form of nephrogenic diabetes insipidus (NDI).

Gene Name: Aqp2

ID gène: 25386

NCBI Accession: NP_037041

UniProt: P34080

Pathways: Response to Water Deprivation