COBRA1 anticorps

N° du produit ABIN6657338

Détail du produit anti-COBRA1 anticorps

Antigène: COBRA1 (Cofactor of BRCA1 (COBRA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp COBRA1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: Anti-COBRA 1 antibody was Protein G purified from culture supernatant. This antibody is directed against human COBRA 1. Reactivity is expected against mouse and rat sources. Cross-reactivity from other sources has not been determined.

Immunogène:

Immunogen: Anti-COBRA1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant full length human COBRA1 purified from E.coli.

Immunogen Type: Recombinant Protein

Clone: F7E4

Isotype: IgG1

Information d'application

Indications d'application:

Application Note: Anti-COBRA 1 antibody is suitable for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 62 kDa in size corresponding to COBRA1 proteins in neonatal rat brain lysate or other appropriate lysates.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Détails sur COBRA1

Antigène: COBRA1 (Cofactor of BRCA1 (COBRA1))

Autre désignation: COBRA 1 (COBRA1 Produits)

Synonymes: anticorps LOC100219583, anticorps COBRA1, anticorps NELF-B, anticorps bZ1O1.4, anticorps cobra1, anticorps cobra2, anticorps fe01e12, anticorps wu:fe01e12, anticorps zgc:55628, anticorps MGC131073, anticorps Cobra1, anticorps RGD1307832, anticorps A730008L03Rik, anticorps AB041607, anticorps AI663983, anticorps Nelf-b, anticorps cofactor of BRCA1, anticorps negative elongation factor complex member B, anticorps negative elongation factor complex member B L homeolog, anticorps LOC100219583, anticorps NELFB, anticorps nelfb, anticorps nelfb.L, anticorps Nelfb

Sujet:

Synonyms: COBRA1, Negative elongation factor B, NELF-B, Cofactor of BRCA1

Background: COBRA 1 antibody reacts with COBRA1 (cofactor of BRCA1) also known as NELF-B, which is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription. COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis. Anti-COBRA 1 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: COBRA1

ID gène: 25920

UniProt: Q8WX92