Retinoic Acid Receptor alpha anticorps (N-Term)

N° du produit ABIN6657357

N° du produit (Fournisseur): 209-301-e25

Cet anticorps Souris Monoclonal détecte spécifiquement Retinoic Acid Receptor alpha dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Retinoic Acid Receptor alpha anticorps (N-Term) (ABIN6657357)

Antigène: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoic Acid Receptor alpha est non-conjugé

Application: Western Blotting (WB)

Clone: 763

Détail du produit anti-Retinoic Acid Receptor alpha anticorps

Épitope: N-Term

N° du produit (Fournisseur): 209-301-e25

Fournisseur: Rockland

Fonction: Retinoic Acid Receptor alpha Antibody

Réactivité croisée (Details): Retinoic Acid Receptor alpha antibody was Protein G purified from cell culture supernatant.

Purification: Anti-Retinoic Acid Receptor alpha antibody detects Retinoic Acid Receptor alpha.

Immunogène: Anti-Retinoic Acid Receptor alpha was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the N-terminal region of RAR-alpha.

Isotype: IgG1

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 1:1000

Commentaires:

Anti-Retinoic Acid Receptor alpha antibody is tested for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to expected molecular weight for RAR-α proteins in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur Retinoic Acid Receptor alpha

Antigène: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Autre désignation: Retinoic Acid Receptor alpha

Sujet:

Synonyms: mouse anti-Retinoic Acid Receptor alpha Antibody, mouse anti-RAR-alpha antibody, RAR-alpha, Nuclear receptor subfamily 1 group B member 1, NR1B1, Retinoic Acid Receptor, α-Isotype

Background: Retinoic Acid Receptor alpha antibody detects RAR alpha. Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Gene Name: RARA

ID gène: 5914

UniProt: P10276

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins