Desmin anticorps

N° du produit ABIN6657489

N° du produit (Fournisseur): 200-301-p35

Cet anticorps Souris Monoclonal détecte spécifiquement Desmin dans WB, IHC et ELISA. Il présente une réactivité envers Porc.

Aperçu rapide pour Desmin anticorps (ABIN6657489)

Antigène: Desmin (DES)

Reactivité: Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: DE-U-10

Détail du produit anti-Desmin anticorps

N° du produit (Fournisseur): 200-301-p35

Fournisseur: Rockland

Fonction: Desmin Antibody

Réactivité croisée (Details): This product reacts with human, mouse, rat, and rabbit.

Purification: Anti-Desmin antibody was purified from mouse ascites by protein A chromatography.

Immunogène: Desmin antibody was produced in mice by repeated immunizations with desmin from pig stomach.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA_Dilution: 1:20,000

Immunohistochemistry_Dilution: 1:100-1:500

Western_Blot_Dilution: 2 μg/mL

Commentaires:

Anti-Desmin is tested for Immunohistochemistry -P and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~53.5 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Neutral PBS

Reconstitution_Volume: 1.0 mL

Buffer:

Buffer: 1.2 % sodium acetate

Stabilizer: 2 mg BSA

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin

Sujet:

Synonyms: CMD1I, CSM1, CSM2, intermediate filament protein

Background: Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. DES gene encodes desmin, a muscle-specific cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball (1992) found that desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al. (1989) localized the gene to 2q35. Desmin mutation responsible for idiopathic dilated cardiomyopathy. This antibody is suitable for researchers interested in cancer research, cardiovascular diseases, neurodegenerative diseases, cell adhesion research, and cytoskeletal signaling research.

Gene Name: DES

ID gène: 396725

NCBI Accession: NP_001001535

UniProt: P02540