CD40 Ligand anticorps (PE)

N° du produit ABIN6657774

N° du produit (Fournisseur): 200-b08-n91

Cet anticorps Hamster Monoclonal détecte spécifiquement CD40 Ligand dans FACS et IHC. Il présente une réactivité envers Souris.

Aperçu rapide pour CD40 Ligand anticorps (PE) (ABIN6657774)

Antigène: CD40 Ligand (CD40LG)

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 Ligand est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: MR1

Détail du produit anti-CD40 Ligand anticorps (PE)

N° du produit (Fournisseur): 200-b08-n91

Fournisseur: Rockland

Fonction: CD154 (CD40L) Phycoerythrin Antibody

Réactivité croisée (Details): Cross reactivity with CD154 from other sources has not been tested.

Purification: Phycoerythrin conjugated CD154 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD154.

Stérilité: Sterile filtered

Immunogène: Anti-CD154 Antibody (Monoclonal) was produced by repeated immunizations with Activated mouse Th1 clone D1.6.

Isotype: IgG

Labeling Ratio: 1-2

Information d'application

Indications d'application:

Immunohistochemistry_Dilution: User Optimized

Flow_Cytometry_Dilution: 10 μL/10^6 cells (0.1 μg)

Commentaires:

Anti-CD154 is tested for FLOW and useful for Immunohistochemistry using mouse spleen cells, or an appropriate cell type (where indicated). Researchers should determine optimal titers for applications that are not stated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.09 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Date de péremption: 6 months

Détails sur CD40 Ligand

Antigène: CD40 Ligand (CD40LG)

Autre désignation: CD154(CD0L)

Sujet:

Synonyms: CD40 ligand, CD40-L, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD154, Cd40lg, Cd40l, Tnfsf5

Background: CD154 is a 39 kD TNF superfamily member also known as CD40 ligand, gp39, T-BAM, TRAP, and Ly-62. CD154 is an accessory molecule expressed predominantly on activated CD4+ lymphocytes that bind CD40. CD154 plays an important role in T-B cell costimulation. The MR1 antibody has been reported to inhibit the activation of T and B lymphocytes in vitro and antigen-specific lymphocyte responses in vivo.

Gene Name: Cd40lg

ID gène: 21947

NCBI Accession: NP_035746

UniProt: P27548

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints