CD40 anticorps (N-Term)

N° du produit ABIN6657891

N° du produit (Fournisseur): 600-401-p53

Cet anticorps Lapin Polyclonal détecte spécifiquement CD40 dans WB. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour CD40 anticorps (N-Term) (ABIN6657891)

Antigène: CD40

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD40 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD40 anticorps

Épitope: N-Term

N° du produit (Fournisseur): 600-401-p53

Fournisseur: Rockland

Fonction: CD40 Antibody

Réactivité croisée (Details): Anti-CD40 antibody is directed against mouse CD40 protein.

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogène: CD40 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the N-terminal of mouse CD40.

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 0.5 μg/mL

Commentaires:

Anti-CD40 is tested for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~32.1 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 200μL

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

Preservative: 0.05 mg Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. After reconstitution, at 4°C for one month. Aliquot and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CD40

Antigène: CD40

Autre désignation: CD40

Sujet:

Synonyms: B-cell surface antigen CD40,Bp50,CD40L receptor,CD_antigen=CD40,

Background: CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium .CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin. This antibody is suitable for researchers interested in cancer research.

Gene Name: CD40

ID gène: 21939

NCBI Accession: NP_035741

UniProt: P27512

Pathways: Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints