KDM5B anticorps (Internal Region)

N° du produit ABIN6657904

N° du produit (Fournisseur): 100-401-v92

L’anticorps Lapin Polyclonal anti-KDM5B a été validé pour WB et ELISA. Il convient pour détecter KDM5B dans des échantillons de Souris.

Aperçu rapide pour KDM5B anticorps (Internal Region) (ABIN6657904)

Antigène: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM5B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-KDM5B anticorps

Épitope: Internal Region

N° du produit (Fournisseur): 100-401-v92

Fournisseur: Rockland

Fonction: Jarid1b Antibody

Réactivité croisée (Details): Cross reactivity with Jarid1b from other species not tested.

Purification: Anti-Jarid1b Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Stérilité: Sterile filtered

Immunogène: Anti-Jarid1b Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing an amino acid sequence from the internal part of mouse Jarid1b.

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:100 - 1:200

Western_Blot_Dilution: 1:500

Commentaires:

Anti-Jarid1b Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 175 kDa in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur KDM5B

Antigène: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Autre désignation: Jarid1b

Sujet:

Synonyms: Lysine-specific demethylase 5B, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1

Background: JARID1B is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1B itself may function as a tumor suppressor. Anti-Jarid1b Antibody is ideal for research in Epigenetics, Chromatin Remodeling and Cancer.

Gene Name: Kdm5b

ID gène: 10765

NCBI Accession: NP_006609

UniProt: Q80Y84

Pathways: L'effet Warburg