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SIX3 anticorps (Internal Region)

SIX3 Reactivité: Souris WB, ELISA, IHC, FM Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6657912
  • Antigène Voir toutes SIX3 Anticorps
    SIX3 (Sine Oculis-Related Homeobox 3 (SIX3))
    Épitope
    • 15
    • 8
    • 8
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 49
    • 18
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Souris
    Hôte
    • 48
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 51
    • 2
    Polyclonal
    Conjugué
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SIX3 est non-conjugé
    Application
    • 45
    • 21
    • 13
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
    Purification
    This product was affinity purified from monospecific antiserum by immunoaffinity chromatography.  This antibody reacts with mouse Six3.   Cross-reactivity with Six3 from other sources has not been determined.
    Immunogène

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse Six3 protein.

    Immunogen Type: Peptide

    Isotype
    IgG
    Top Product
    Discover our top product SIX3 Anticorps primaire
  • Indications d'application

    Immunohistochemistry Dilution: 1:100-1:250

    Application Note: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 37 kDa in size corresponding to Six3 by western blotting in the appropriate cell lysate or extract.

    ELISA Dilution: 1:10,000-1:15,000

    Western Blot Dilution: 1:500 - 1:2,000

    IF Microscopy Dilution: 1:200 - 1:1,000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    0.01 % (w/v) Sodium Azide

    Stabilizer: None

    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Li, Xie, He, Zhou, Gao, Liu, Pan, Ge, Peng, Zhong: "Generation of Retinal Organoids with Mature Rods and Cones from Urine-Derived Human Induced Pluripotent Stem Cells." dans: Stem cells international, Vol. 2018, pp. 4968658, (2018) (PubMed).

    Diacou, Zhao, Zheng, Cvekl, Liu: "Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation." dans: Cell reports, Vol. 25, Issue 9, pp. 2510-2523.e4, (2018) (PubMed).

    Xu, Liang, Song, Zhang, Lindtner, Li, Wen, Liu, Guo, Qi, Wang, Wang, Li, You, Wang, Chen, Feng, Rubenstein, Yang: "SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression." dans: Development (Cambridge, England), Vol. 145, Issue 14, (2018) (PubMed).

  • Antigène
    SIX3 (Sine Oculis-Related Homeobox 3 (SIX3))
    Autre désignation
    Six3 (SIX3 Produits)
    Synonymes
    anticorps HPE2, anticorps SIX3, anticorps cb347, anticorps six3.2, anticorps six6, anticorps E130112M24Rik, anticorps Six3a, anticorps Six3alpha, anticorps Six3b, anticorps Six3beta, anticorps six3, anticorps six3.1, anticorps wu:fc10a08, anticorps SIX homeobox 3, anticorps SIX homeobox 3b, anticorps sine oculis-related homeobox 3, anticorps SIX homeobox 3a, anticorps sine oculis homeobox homolog 3, anticorps SIX3, anticorps six3b, anticorps Six3, anticorps six3a, anticorps six3
    Sujet

    Synonyms: rabbit anti-Six3 antibody, Six-3, Six 3, Homeobox protein SIX3, Sine oculis homeobox homolog 3

    Background: Six3 (also known as sine oculis homeobox homolog 3) is involved in the development of the visual system and forebrain.  Six3 is a nuclear protein that is reported to exist in two forms by alternative splicing of the gene product.  Six3 is first expressed at E6.5 of mouse embryonic development around the anterior border. At E8.5, expression is found over the anterior neural plate. At E9.5, it is in the diencephalic part of the ventral forebrain, optic vesicles, olfactory placodes and Rathke's pouch. In later stages, Six3 is present in hypothalamus, eyes and pituitary.

    Gene Name: Six3

    ID gène
    20473, 59939908
    UniProt
    Q62233
    Pathways
    Protein targeting to Nucleus
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