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Tryptophan Hydroxylase 1 anticorps

Cet anticorps anti-Tryptophan Hydroxylase 1 est un anticorps Mouton Polyclonal détectant Tryptophan Hydroxylase 1 dans WB et IHC. Adapté pour Lapin.
Rockland
N° du produit ABIN6658049
N° du produit (Fournisseur): 600-601-c96

Aperçu rapide pour Tryptophan Hydroxylase 1 anticorps (ABIN6658049)

Antigène

Voir toutes Tryptophan Hydroxylase 1 (TPH1) Anticorps
Tryptophan Hydroxylase 1 (TPH1)

Reactivité

  • 83
  • 53
  • 48
  • 10
  • 5
  • 4
  • 3
  • 3
  • 3
Lapin

Hôte

  • 82
  • 9
  • 5
Mouton

Clonalité

  • 87
  • 9
Polyclonal

Conjugué

  • 55
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Tryptophan Hydroxylase 1 est non-conjugé

Application

  • 75
  • 39
  • 28
  • 17
  • 10
  • 8
  • 6
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • N° du produit (Fournisseur)

    600-601-c96

    Fournisseur

    Rockland

    Fonction

    Tryptophan Hydroxylase Antibody

    Réactivité croisée (Details)

    Anti-Tryptophan Hydroxylase antibody is directed against Tryptophan 5-hydroxylase 1.

    Purification

    Tryptophan Hydroxylase antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.

    Immunogène

    Anti-Tryptophan Hydroxylase Antibody was produced in sheep by repeated immunizations with recombinant rabbit tryptophan hydroxylase, isolated as inclusion bodies from E. coli and purified by preparative SDS-PAGE.

    Isotype

    IgG
  • Indications d'application

    Immunohistochemistry_Dilution: 1:1000

    Western_Blot_Dilution: 1:1000

    Commentaires

    Anti-Tryptophan Hydroxylase (Sheep) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to tryptophan hydroxylase protein in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

    Date de péremption

    12 months
  • Antigène

    Tryptophan Hydroxylase 1 (TPH1)

    Autre désignation

    Tryptophan Hydroxylase

    Sujet

    Synonyms: Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1

    Background: Tryptophan Hydroxylase antibody detects Tryptophan Hydroxylase. TPH catalyzes the first step in the biosynthesis of serotonin and melatonin. Thus, expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis. Anti-Tryptophan Hydroxylase antibody is ideal for investigators involved in Cell Signaling and Neuroscience research.

    Gene Name: TPH1

    ID gène

    100101558

    NCBI Accession

    NP_001093425

    UniProt

    P17290

    Pathways

    Feeding Behaviour
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