GRIN2B anticorps (N-Term)

N° du produit ABIN6658131

N° du produit (Fournisseur): 200-301-g23

Cet anticorps Souris Monoclonal détecte spécifiquement GRIN2B dans WB, IHC, IP, IF et FM. Il présente une réactivité envers Rat.

Aperçu rapide pour GRIN2B anticorps (N-Term) (ABIN6658131)

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GRIN2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Clone: S59-36

Détail du produit anti-GRIN2B anticorps

Épitope: N-Term

N° du produit (Fournisseur): 200-301-g23

Fournisseur: Rockland

Fonction: NR2B Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with NR2B from human, mouse, and rat based on 100 % homology with the immunizing sequence.

Purification: Anti-NR2B Antibody was purified by Protein G chromatography.

Stérilité: Sterile filtered

Immunogène: NR2B Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding near the extracellular N-terminus region of rat NR2B.

Isotype: IgG2b

Information d'application

Indications d'application:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

IF_Microscopy_Dilution: 1.0-10 μg/mL

Western_Blot_Dilution: 1-10 μg/mL

Commentaires:

Anti-NR2B Antibody is tested for use in WB, IHC, IF, and IP. Expect a band approximately ~166kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur GRIN2B

Antigène: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Autre désignation: NR2B

Sujet:

Synonyms: NMDAR2B, hNR3, MGC142180, glutamate receptor subunit epsilon-2, NR3, NR2B, N-methyl D-aspartate receptor subtype 2B

Background: NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation. Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain, NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics.

Gene Name: Grin2b

ID gène: 24410

NCBI Accession: NP_036706

UniProt: Q00960

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity