SYN1 anticorps (pSer603)

N° du produit ABIN6658200

N° du produit (Fournisseur): 612-401-c95

Cet anticorps Lapin Polyclonal détecte spécifiquement SYN1 dans WB. Il présente une réactivité envers Rat et a été mentionné dans 2+ publications.

Aperçu rapide pour SYN1 anticorps (pSer603) (ABIN6658200)

Antigène: SYN1 (Synapsin I (SYN1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SYN1 anticorps

Épitope: pSer603

N° du produit (Fournisseur): 612-401-c95

Fournisseur: Rockland

Fonction: Synapsin I phospho S603 Antibody

Réactivité croisée (Details): The antibody detects Synapsin I that is phosphorylated at S603.

Purification: Anti-Synapsin I pS603 antibody is directed against bovine Synapsin I.

Immunogène: Anti-Synapsin I pS603 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser603 of Synapsin I.

Isotype: IgG

Information d'application

Indications d'application: Optional[Neutralization_Dilution]: 1:1000

Commentaires:

Anti-Synapsin I pS603 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 78 kDa in size corresponding to synapsin I doublet protein phosphorylated at Ser603.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-SYN1 (ABIN6658200)

Engholm-Keller, Waardenberg, Müller, Wark, Fernando, Arthur, Robinson, Dietrich, Schoch, Graham: "The temporal profile of activity-dependent presynaptic phospho-signalling reveals long-lasting patterns of poststimulus regulation." dans: PLoS biology, Vol. 17, Issue 3, pp. e3000170, (2019) (PubMed).

Hammond, Lu, Gelbard: "Platelet Activating Factor Enhances Synaptic Vesicle Exocytosis Via PKC, Elevated Intracellular Calcium, and Modulation of Synapsin 1 Dynamics and Phosphorylation." dans: Frontiers in cellular neuroscience, Vol. 9, pp. 505, (2016) (PubMed).

Détails sur SYN1

Antigène: SYN1 (Synapsin I (SYN1))

Autre désignation: Synapsin I

Sujet:

Synonyms: Synapsin I, SYN1

Background: Synapsin I pS603 antibody is directed against rat Synapsin I, whcih plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 603 is the site on synapsin I that is phosphorylated by calcium calmodulin kinase II and by p21-activated kinases. Phosphorylation of this site is thought to regulate synaptic vesicle function. Anti-Synapsin I pS603 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: SYN1

ID gène: 24949

NCBI Accession: NP_001104252

UniProt: P09951