APP anticorps (C-Term)

N° du produit ABIN6658203

N° du produit (Fournisseur): 612-401-253

Cet anticorps Lapin Polyclonal détecte spécifiquement APP dans WB et ELISA. Il présente une réactivité envers Rat.

Aperçu rapide pour APP anticorps (C-Term) (ABIN6658203)

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-APP anticorps

Épitope: C-Term

N° du produit (Fournisseur): 612-401-253

Fournisseur: Rockland

Fonction: Beta Amyloid Antibody

Réactivité croisée (Details): The antibody is directed against rat Beta Amyloid.

Purification: Anti-Beta Amyloid Antibody is directed against rat Beta Amyloid proteins.

Immunogène: Anti-Beta Amyloid Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region.

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-Beta Amyloid antibody is tested for use in ELISA, Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 115 kDa in size corresponding to the APP protein in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur APP

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Autre désignation: APP

Sujet:

Synonyms: Amyloid beta A4 protein, ABPP, Alzheimer disease amyloid A4 protein homolog, Amyloidogenic glycoprotein, A-beta, ABeta antibody

Background: Anti-Beta Amyloid antibody recognizes beta amyloid protein also called amyloid precursor protein (APP). A large body of evidence has implicated the APP in the pathogenesis of Alzheimer's disease (AD). The phosphorylation of APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD. Anti-Beta Amyloid antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: APP

ID gène: 54226

NCBI Accession: NP_062161

UniProt: P08592

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour